CHM 246 Organic Chemistry II Laboratory
Course Title: CHM 246: Organic Chemistry II Laboratory
Course Description
Introduces various methods and procedures used in present day organic laboratories. Covers the general techniques, organic synthesis, and the use of common spectroscopic instrumentation; synthesizing a variety of compounds; and analyzing the products through physical properties and spectroscopy. Part II of II. Lecture 1 contact hour. Lab 3 contact hours. Total 4 contact hours. 2 credits.
General Course Purpose
Explores the physical properties and reactivity of organic compounds including common methods of separation, purification, and instrumental analysis. (Continued from CHM 245)
Course Prerequisites/Corequisites
Prerequisite: CHM 245; Corequisite: CHM 242.
Course Objectives
Upon completing the course, the student will be able to:
Continued: Safety in the Organic Laboratory
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Use proper procedures and regulations for safe handling and use of chemicals in the organic chemistry laboratory
Continued: Lab notebook
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Maintain a lab notebook and demonstrate proper recording, organization, and interpretation of scientific data
Application of Laboratory techniques from CHM 245
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Formulate and perform the laboratory synthesis, purification, and characterization of the organic compounds studied; applying techniques covered in CHM 245.
1H and 13C NMR Spectroscopy
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Interpret spectra and identify compounds
Synthesis and analysis
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Preparation and analysis of a variety of organic compounds.
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Perform theoretical yield, percent yield, and percent recovery calculations.
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Potential reactions to be studied include: Grignard reaction, EAS reaction, Fischer esterification, aldol condensation, polymers
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Additional lab experiments that could be included: Synthesis of biodiesel,
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Diels-Alder, oxidation/reduction reactions, free radical halogenation, synthesis of aspirin, hydroboration-oxidation of alkenes
Mechanism
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Propose mechanisms for all reactions.
Theoretical understanding
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Explain the theoretical basis of all techniques and state reasons for use of specific reagents.
Major Topics to be Included
Continued: Safety in the Organic Laboratory
Continued: Lab notebook
Application of Laboratory techniques from CHM 245
1H and 13C NMR Spectroscopy
Synthesis and analysis
Mechanism
Theoretical understanding